Neglected Tropical Diseases (NTDs)


Community lay workers at home with
participants in the MANAS trial, (c) Vikram Patel

The Group has significant research activity on neglected tropical diseases, with ongoing research projects on trachoma, visceral leishmaniasis, helminth infections, and epilepsy. Several important studies were completed in 2011-12, including innovative trials of the management of trachomatous trichiasis in Ethiopia, a trial of short course combination treatment for visceral leishmaniasis, now incorporated into treatment guidelines for East Africa and completion of a 5-year follow-up of the Entebbe Mother and Baby Study, which found no association between helminth infections and their treatment on incidence of other infectious diseases and eczema.

Key Publications:

Edwards T, Smith J, Sturrock HJ, Kur LW, Sabasio A, Finn TP, Lado M, Haddad D, Kolaczinski JH (2012) Prevalence of trachoma in Unity State, South Sudan: results from a large-scale population-based survey and potential implications for further surveys. PLoS Negl Trop Dis, 6(4):e1585. doi: 10.1371/journal.pntd.0001585.

Musa A, Khalil E, Hailu A, Olobo J, Balasegaram M, Omollo R, Edwards T, Rashid J, Mbui J, Musa B, Abuzaid AA, Ahmed O, Fadlalla A, El-Hassan A, Mueller M, Mucee G, Njoroge S, Manduku V, Mutuma G, Apadet L, Lodenyo H, Mutea D, Kirigi G, Yifru S, Mengistu G, Hurissa Z, Hailu W, Weldegebreal T, Tafes H, Mekonnen Y, Makonnen E, Ndegwa S, Sagaki P, Kimutai R, Kesusu J, Owiti R, Ellis S, Wasunna M (2012) Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial. PLoS Negl Trop Dis 6(6):e1674. doi: 10.1371/journal.pntd.0001674.

Staff working on NTDs:


Theme Leader
Professor Peter Smith








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