The MRC-funded Tropical Epidemiology Group (TEG) initiates epidemiological research and provides epidemiological and statistical expertise for research projects in resource-poor settings. The mission of the Group has remained the same over the past 40 years – to conduct research on the epidemiology and control of diseases of major public health importance in developing countries. We focus primarily on statistics and epidemiology with an emphasis on conducting rigorously designed intervention studies, including i) randomised controlled trials (RCTs) to identify effective interventions against these diseases and (ii) research strategies to implement such interventions. Our expertise is constantly evolving and we have established expertise in mathematical modelling, data management, and public health. In addition we have good links with social scientists and health economists which adds a further dimension to our work.